Human Growth Hormone Supplements HMG Injection For Fertility
What are gonadotrophins?
Gonadotrophins are injectable hormones that can be used to treat
fertility problems in women and men. Gonadotrophins help women to
ovulate and men to improve their sperm count.
What's the success rate of gonadotrophins?
Up to 85 per cent of women with an ovulation problem will ovulate
after using gonadotrophins. About 23 per cent of women with
clomifene-resistant PCOS conceive while using gonadotrophins and
about 20 per cent have a live birth.
Other factors that can affect conception are:
the time in your cycle you have sex
the speed and ability to move (motility) of your partner's sperm
Gonadotrophins are often used in IVF treatments because controlling
the development and release of mature eggs from your ovaries
increases your chance of success.
Are gonadotrophins right for me?
You are most likely to be offered these drugs if you:
Have polycystic ovary syndrome and have not ovulated in response to
Are having assisted-conception treatments, such as in-vitro
fertilisation (IVF) or intracytoplasmic sperm injection (ICSI).
If your partner has a hormonal imbalance linked to a low sperm
count, or poor sperm quality or motility, he may be offered
Talk to your doctor about your chances of success using these
drugs. If you're paying for your treatment, be clear about how much
these drugs will cost. This way you can weigh up the pros and cons
as best you can before beginning treatment.
How do gonadotrophins work?
The two hormones your body produces that are crucial for ovulation
to take place are luteinising hormone (LH) and follicle-stimulating
Gonadotrophins are injectable forms of these hormones. They
directly stimulate your ovaries to produce and ripen eggs.
The type of gonadotrophins that have been in use for the longest
time contain both FSH and LH. These are called human menopausal
Some drugs, called follitropins, now contain only purified FSH.
There is not much evidence to suggest that one type of
gonadotrophin is better than another at stimulating the ovaries to
produce mature eggs, although there may be differences in the cost
or availability of some types.
You'll have gonadotrophins in conjunction with another hormone
called human chorionic gonadotrophin (hCG). This hormone completes
the final stage of egg maturation and can trigger ovulation, too.
How long will I need to be treated with gonadotrophins?
You can begin treatment any time when you're not ovulating. Your
course of injections will continue daily for about 12 days each
month, depending on how long it takes for your eggs to mature.
Your doctor might teach you how to give yourself the injections so
you don't have to travel to the clinic every day. You may want your
doctor to show your partner how to do the injections, if you don't
want to do it yourself.
While you're having the injections, your doctor will monitor you to
see when you're likely to ovulate. This means you'll have frequent
ultrasound scans to check your ovaries. The scans will be carried
out using a probe inserted into your vagina and shouldn't cause you
any discomfort. You may need to have blood tests to check the
levels of your hormones, too.
When the scan shows that your eggs are mature, you'll be given an
injection of hCG to trigger ovulation. Ovulation usually occurs
between 24 hours and 36 hours after the hCG injection.
You and your partner will need to time sex soon after your
injection. If you're having IVF, the egg collection procedure will
be scheduled for about 36 hours after your injection.
If you're being treated for an ovulation disorder, you're likely to
have a maximum of three to six drug cycles. Success rates don't
improve if you take the drugs for a longer time. If you try three
times or more and don't get pregnant, your doctor may increase the
dose or suggest another kind of treatment.
Do gonadotrophins have any side-effects?
It's possible that you may experience any of the following
an allergic reaction to the drug
soreness or reaction at the injection site
You may find that giving yourself an injection directly into your
muscle, probably your thigh, is difficult as it requires a long
needle. The newer, purer gonadotrophins cause fewer side-effects
and can be injected using smaller needles under your skin.
Taking these fertility drugs can be an emotionally intense process.
As well as all the injections, you'll need to have frequent
There's a risk with treatment involving gonadotrophins, and hCG in
particular, of developing ovarian hyperstimulation syndrome (OHSS).
This is when your ovaries rapidly swell to several times their
usual size. Your ovaries may also leak fluid into your abdominal
Most cases of OHSS are mild. They result in:
mild abdominal pain
Severe OHSS is signalled by:
sudden, severe pain in your belly
thirst and other symptoms of dehydration
If a scan shows that your ovaries are developing too many eggs,
you'll be advised not to have sex or exercise strenuously. This is
to avoid the risk of injury to your swollen ovaries.
If you're trying to get pregnant without assisted conception, it
can be disappointing to have to abandon a cycle of treatment. It's
worth being cautious, though, as you also risk having a multiple
pregnancy. This can lead to complications for you and your babies.
HongKong Biosuper Health Tech. Co., Ltd has a well-established
quality system, which meets the requirements of the international
quality standards GMP.